Memory storage in the human brain is one of the greatest mysteries of neuroscience. Knowing how and where the brain stores our memories is highly sought after information. Computer scientists want to know so they can make better memory storage devices, philosophers want to know so they can better hypothesize whether or not the mind is separate from the brain, and neuroscientists want to know so they can eradicate, or at least alleviate, amnesia. . There are two particularly famous amnesiacs, known as HM and EP, who, in an effort to better understand their condition, scientists have developed new tests and procedures to evaluate brain function and attempt to determine which parts of the brain are responsible of memory. The purpose of this work is to explain the conditions of HM and PE and examine how these cases have contributed to the exploration of storage and memory disorders. HM was riding his bicycle one day at the age of nine when he had an accident and collided. his head. His accident caused a series of seizures that started out mild and relatively infrequent, but became increasingly intense and more frequent. It got to the point that these seizures "were so disturbing that he was no longer able to function" (Rudy 238). When he was 27, HM underwent surgery at the hands of Dr. William Scoville. Dr. Scoville drilled a hole above each of HM's eyes and "lifted the front of HM's brain... while a metal straw sucked out most of the hippocampus, along with much of the surrounding medial temporal lobes" (Foer 78-9). This procedure alleviated the epilepsy almost completely, but it was soon discovered that HM's memory was permanently damaged. Dr. Brenda Milner determined that the surgery caused anterograde amnesia. HM could not form... halfway through the paper... the task of assessing the extent of HM's anterograde amnesia. He asked HM to trace the shape of a star on a piece of paper in front of a mirror, only being able to see the star in the mirror. On the first day of testing, he made many mistakes, just like anyone attempting a task for the first time with the amount of hand-eye coordination this experiment requires. Between trials, when asked if he had done this task before, he stated that he had not, because he could not remember doing it. But by the end of the first day his results had improved significantly. On the second day he did even better, and in each of the 10 trials performed on the third day HM made almost zero errors (Rudy, The Neurobiology of Learning and Memory). This shows that while HM had lost the function of his episodic memory system, he was still able to "acquire a new motor skill" (Rudy, 239).
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